Immunomodulatory Therapy for Rasmussen Syndrome
نویسندگان
چکیده
منابع مشابه
Rasmussen Syndrome and Other Inflammatory Epilepsies.
An underlying immune basis is emerging in an increasing number of epileptic and encephalopathic syndromes. The immunopathological mechanisms may be categorized into antibody-mediated, T-cell cytotoxicity, and microglia-induced degeneration. The immune basis in Rasmussen syndrome is thought to be T-cell mediated. Antibodies to extracellular and intracellular epitopes are implicated in limbic and...
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Investigators from Rothschild Foundation Hospital in Paris report language outcome in children after (left) dominant-hemisphere hemispherotomy for Rasmussen Syndrome.
متن کاملRasmussen syndrome: An Argentinean experience in 32 patients
PURPOSE The aim of this study is to analyze the electroclinical features, treatment, and evolution of patients with Rasmussen syndrome (RS). MATERIALS AND METHODS We conducted a retrospective, descriptive study in 32 consecutive patients with RS followed between 1990 and 2012. RESULTS Twenty boys and 12 girls were included in the study. The mean and median ages at onset of the seizures were...
متن کاملTiming of surgery in rasmussen syndrome: is patience a virtue?
Rasmussen syndrome affects previously normal people and forever changes their lives and the lives of their families. Although understood as a probable autoimmune condition, medical treatment remains limited and surgery remains the only cure, although with inevitable functional consequences. Difficulties remain in deciding on the optimal timing of surgery. Here, we review data available to aid c...
متن کاملLimited chronic focal encephalitis: another variant of Rasmussen syndrome?
OBJECTIVE To describe a more limited and less malignant form of Rasmussen encephalitis (RE). METHODS Three subjects (all women; 37, 31, and 32 years of age) developed childhood or late onset chronic focal encephalitis, with a relatively nonprogressive form of the disorder. RESULTS In our patients, clinical features were dominated by partial seizures without marked focal motor deficit and in...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 2013
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-27-10-9